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The stability of these mutants is ~3 kcal/mole lower relatively to the WT (20-22), and the internal flexibility of the polypeptide is considerably larger, particularly with I7S and F110S (18)
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The highly purified HuBChE was stored at 4°C after lyophilization from 10 mM sodium phosphate, pH 8
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The optimized S^sup 2^^sub ^s values have an average of 0
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