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In a well-known example, the higher cationicity of spermine^sup 4+^ compared to spermidine^sup 3+^, which evidently makes spermine bind more strongly to negatively charged DNA, determines the higher DNA compaction potential of spermine (Takahashi et al
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. This apparent K^sub d^, which reflects protein-protein associations on a confined membrane surface, is predicted to be ~2 orders of magnitude weaker when the proteins are free to associate in solution (see Runnels and Scarlata, 1999)
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. A study of 126 women enrolled in methadone treatment found that all the women who lived with a crack-using partner used crack themselves (34)
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. N Engl J Med 2003;348:1625-1638
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. For example, a patient taking neuroleptics who relapses to stimulant medications is at risk of hyperpyrexia
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- In the final structure, the interface domain is hidden in a hydrophobic, packed core surrounded by the other domains, as demonstrated by crystallographic studies of human GR (Schulz et al
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. Given a new set of Cartesian coordinates from step 4, we calculate the energy for the new conformation
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.The native state of HuBChE is also stabilized by the kosmotropic sodium phosphate buffer; its flexibility is reduced and its resilience increased over a large temperature range as established by neutron scattering (44)
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. Bis-ANS was omitted from this binding study due to the promiscuous behavior in terms of fluorescence response; it essentially binds to any conformational state of TTR
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.In line with the previous analysis of the functional elements, CD4-F43 shows a large intraresidue entropy reduction upon complexation (Fig
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. The number of ova in the subsamples were counted and absolute fecundity was estimated by using the following algorithm:[MATHEMATICAL EXPRESSION NOT REPRODUCIBLE IN ASCII
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. Other projects supported by the group include psychiatrist Charles Grub's psilocybin research with terminal cancer patients at UCLA; Charleston, South Carolina, psychiatrist Michael Mitohefer's study of MDMA as a treatment for posttraumatic stress disorder; and University of Arizona at Tucson psychiatrist Francisco Moreno's study of psilocybin as a treatment for obsessive compulsive disorder
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