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Eocating monovalent cations in the grooves of B-DNA
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- Predissociated Dimers and Molten Globule Monomers in the Equilibrium Unfolding of Yeast Glutathione ReductaseLouzada, Paulo RobertoABSTRACTThe equilibrium unfolding of dimeric yeast glutathione reductase (GR) by guanidine hydrochloride (GdnHCl) was investigated
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.Here, p^sub A^ and p^sub B^ are the populations of the states A and B, ?^sub ex^ = ?^sub A^ - ?^sub B^ is the chemical shift difference between the two states, k^sub ex^ = k^sub A[arrow right]B^ / p^sub B^ = k^sub B[arrow right]A^ / p^sub A^ is the rate constant for the exchange process, ? is the delay of the ?-180°-? CPMG block and ?^sub I^ is the frequency of nucleus I
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