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- That the intermediate is monomeric in nature is also evident from its fluorescence emission ?^sub max^, which is similar to its fully folded monomeric state, characterized earlier (23) (Fig
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.The influence of inhibitor-binding on global enzyme molecular dynamicsAlthough several studies using different techniques have shown a modification of global protein molecular dynamics on an Angström-nanosecond scale upon inhibitor-binding, we were not able to detect any significant differences between the native and the inhibited HuBChE, at comparable degrees of hydration, up to ~334 K (61°C)
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